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PUBLICATIONS
Building the future one figure at a time
Kumar A, Thomas S, Wong K, Lo Sardo V, Cheah D, Hou Y-H, Placone JK, Tenerelli K, Ferguson W, Torkamani A, Topol E, Baldwin KK, and Engler AJ. Mechanical activation of non-coding-RNA-mediated regulation of disease-associated phenotypes in human cardiomyocytes. Nature Biomedical Engineering. 2019, in press. doi: 10.1038/s41551-018-0344-5.
Lai JI, Nachun D, Petrosyan L, Throesch B, Campau E, Gao F, Baldwin KK, Coppola G, Gottesfeld JM, Soragni E. Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures. J Biol Chem. 2018 Dec 14. pii: jbc.RA118.006515. doi: 10.1074/jbc.RA118.006515. PMID: 30552117
Lo Sardo V, Chubukov P, Ferguson W, Kumar A, Teng EL, Duran M, Zhang L, Cost G, Engler AJ, Urnov F, Topol EJ, Torkamani A, Baldwin, KK. Unveiling the role of the most impactful cardiovascular risk locus through haplotype editing. Cell. 2018 Dec 13;175(7):1796-1810.e20. doi: 10.1016/j.cell.2018.11.014. Epub 2018 Dec 6.
Tsunemoto RK*, Lee, S*, Szűcs A, Chubukov P, Sokolova I, Blanchard JW, Eade KT, Bruggemann J, Wu C, Torkamani A, Sanna PP, Baldwin, KK. Diverse reprogramming codes for neuronal identity. Nature. 2018 May;557(7705):375-380. PMID: 29743677* these authors contributed equally.
*Blanchard JW, *Xie J, El-Mecharrafie N, Gross S, Lee S, Lerner RA, Baldwin KK. Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries. Nature Biotechnol. 2017 Sep 11. doi: 10.1038/nbt.3963. * these authors contributed equally.
Lo Sardo V, Ferguson W, Erikson GA, Topol EJ, Baldwin KK*, Torkamani A*. Influence of donor age on induced pluripotent stem cells. Nature Biotechnol. 2017 Jan;35(1):69-74. doi: 10.1038/nbt.3749. * these authors contributed equally.
*Hazen JL, *Faust GG, Rodriguez AR, Ferguson WC, Shumilina S, Clark RA, Boland MJ, Martin G, Chubukov P, Tsunemoto RK, Torkamani A, Kupriyanov S, Hall IM, Baldwin KK. The Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning. Neuron. 2016 Mar 16;89(6):1223-36. doi: 10.1016/j.neuron.2016.02.004. * these authors contributed equally.
Cao Y, Sarria I, Fehlhaber KE, Kamasawa N, Orlandi C, James KN, Hazen JL, Gardner MR, Farzan M, Lee A, Baker S, Baldwin K, Sampath AP, Martemyanov KA. Mechanism for Selective Synaptic Wiring of Rod Photoreceptors into the Retinal Circuitry and Its Role in Vision. Neuron. 2015 Sep 23;87(6):1248-60. doi: 10.1016/j.neuron.2015.09.002.
Hiler D, Chen X, Hazen J, Kupriyanov S, Carroll PA, Qu C, Xu B, Johnson D, Griffiths L, Frase S, Rodriguez AR, Martin G, Zhang J, Jeon J, Fan Y, Finkelstein D, Eisenman RN, Baldwin K, Dyer MA. Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors. Cell Stem Cell. 2015 Jul 2;17(1):101-15. doi: 10.1016/j.stem.2015.05.015.
Quinlan AR, Boland MJ, Leibowitz ML, Shumilina S, Pehrson SM, Baldwin KK, Hall IM. Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming. Cell Stem Cell. 2011 Oct 4;9(4):366-73.
Nityanandam A, Baldwin KK. Advances in reprogramming-based study of neurologic disorders. Stem Cells Dev. 2015 Jun 1;24(11):1265-83. doi: 10.1089/scd.2015.0044.
Boland MJ, Hazen JL, Nazor KL, Rodriguez AR, Martin G, Kupriyanov S, Baldwin KK. Generation of mice derived from induced pluripotent stem cells. J Vis Exp. 2012 Nov 29;(69):e4003.
Ghosh S, Larson SD, Hefzi H, Marnoy Z, Cutforth T, Dokka K, Baldwin KK. Sensory maps in the olfactory cortex defined by long-range viral tracing of single neurons. Nature. 2011 Apr 14;472(7342):217-20.
*Blanchard JW, *Eade KT, Szűcs A, Lo Sardo V, Tsunemoto RK, Williams D, Sanna PP, Baldwin KK. Selective conversion of fibroblasts into peripheral sensory neurons. Nature Neuroscience. 2015 Jan;18(1):25-35. doi: 10.1038/nn.3887. * these authors contributed equally.
Tsunemoto RK, Eade KT, Blanchard JW, Baldwin KK. Forward engineering neuronal diversity using direct reprogramming. EMBO J. 2015 Jun 3;34(11):1445-55. doi: 10.15252/embj.201591402.
*Boland, MJ., *Hazen, J.L., *Nazor, K.L., Rodriguez, A.R., Gifford, W., Martin, G., Kupriyanov, S. Baldwin, KK. Adult Mice Generated from induced pluripotent stem cells. Nature. 2 August 2009 | doi:10.1038/nature08310. *these authors contributed equally.
*Tasic, B., *Nabholz, C.E., Baldwin, K.K., Kim, Y., Rueckert, E.H., Ribich, S.A., Cramer, P., Wu, Q., Axel, R. and Maniatis, T. Promoter choice determines splice site selection in protocadherin alpha and gamma pre-mRNA splicing. Molecular Cell. 2002. 10(1): 21-33. * these authors contributed equally.
*Eggan, K., *Baldwin, K., Tackett, M., Osborne, J., Gogos, J., Chess, A., Axel, R. and Jaenisch, R. Mice cloned from olfactory sensory neurons. Nature. 04 March 2004. 428: 44-49. * these authors contributed equally.
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